Advanced Maternal Grandmother Age is a Risk Factor in Causing Sex Chromosomal Aneuploidy
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چکیده
منابع مشابه
Advanced Maternal Grandmother Age and Maternal Age as Risk Factors for Down Syndrome in a Group of Jordanian Families
Objectives: To study whether advanced maternal age and maternal grandmother age are associated with increased risk of Down syndrome siblings in a group of Jordanian families. Methods: This study was conducted on 127 confirmed Down syndrome cases with the age range of 18 weeks gestation to 15 years old, which were referred between the period of 2005-2008 for cytogenetic analysis at the Cytogenti...
متن کاملMaternal age-specific rates of fetal chromosomal abnormalities in Korean pregnant women of advanced maternal age
OBJECTIVE To evaluate the association of maternal age with occurrence of fetal chromosomal abnormalities in Korean pregnant women of advanced maternal age (AMA). METHODS A retrospective review of the amniocentesis or chorionic villous sampling (CVS) database at Gangnam and Bundang CHA Medical Centers, between January 2001 and February 2012, was conducted. This study analyzed the incidence of ...
متن کاملShould the first-trimester aneuploidy screen be maternal age adjusted? Screening by absolute risk versus risk adjusted to maternal age.
OBJECTIVE To compare the absolute risk (AR) screening approach to the current approach of risk adjusted to maternal age in patients undergoing first-trimester screening (FTS). MATERIAL AND METHODS Three-stage retrospective analysis of 3073 pregnancies that had FTS during 2006-2007. (1) Distribution analysis of AR as defined by (final FTS risk)/(risk by age). (2) Analysis of the screen-positiv...
متن کاملMaternal age-specific risk of non-chromosomal anomalies.
OBJECTIVES To determine the excess risk of non-chromosomal congenital anomaly (NCA) among teenage mothers and older mothers. DESIGN AND SETTING Population-based prevalence study using data from EUROCAT congenital anomaly registers in 23 regions of Europe in 15 countries, covering a total of 1.75 million births from 2000 to 2004. PARTICIPANTS A total of 38,958 cases of NCA that were live bir...
متن کاملPossible risk factors for Down syndrome and sex chromosomal aneuploidy in Mysore, South India
BACKGROUND Down syndrome (DS) and sex chromosomal aneuploidy (SA) are common chromosomal anomalies causing congenital malformations and mental retardation in humans. The well-established risk factor, advanced maternal age, was not found in many of the DS and SA cases in India, while the other possible risk factors have not been well studied. In view of this, the present study has been made. M...
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ژورنال
عنوان ژورنال: INTERNATIONAL JOURNAL OF HUMAN GENETICS
سال: 2007
ISSN: 0972-3757,2456-6330
DOI: 10.31901/24566330.2007/07.04.04